College Basketball Best Bets: Three Favorite Picks for Wednesday, December 7

Another good slate of college basketball games awaits on Wednesday night.

If you haven't already, you should consider signing up for DraftKings ➡️ here ⬅️ as you can turn a $5 pre-game moneyline bet on any game into a free $150 if your team wins. 

RELATED: College Basketball Bet Hub 

College Basketball Best Bets for Wednesday, December 7

Penn State Nittany Lions vs. Michigan State Spartans - 6:30PM ET

Michigan State hobbles into this game off the heels of back to back losses at Notre Dame and vs. Northwestern. Injuries have plagued an already shorthanded MSU squad, as they look visibly worn down from a combination of a tough schedule early and not enough bodies. Penn State is not a fun team to play if you're low on healthy bodies.

The Nittany Lions shoot more threes than anybody in the country, and they make 40% as a team. Michigan State gives up a ton of threes defensively, so Penn State will be licking their chops. Expect MSU's fatigue to factor into play here in the second half, as we like Penn State to run away with it late.

BET: Penn State -3.5 (-110) at DraftKings Sportsbook

🏀 Penn State vs. Michigan State Predictions
📈 Betting preview: Penn State vs. Michigan State

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Florida Gators vs. UConn Huskies - 9:00PM ET

This is a similar spot to the Wisconsin over Maryland pick from yesterday. Undefeated team heads into it's first true road game of the year against a talented squad that needs a marquee win at home. UConn is undoubtedly the better team on paper, but we like the matchup for the Gators here.

In Adama Sanogo's career at UConn, the Huskies are 0-5 in true road games against Top 50 teams on KenPom. Gators center Colin Castleton is averaging 2.9 blocks per game on the season and will make things tough inside. We like Florid to cover here, with a great chance at winning outright.

BET: Florida +4.5 (-110) at DraftKings Sportsbook

🏀 Florida vs. UConn Predictions
📈 Betting preview: Florida vs. UConn

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Pittsburgh Panthers vs. Vanderbilt Commodores - 9:00PM ET

I can't believe I'm saying this out loud (or in writing) but Pitt has been playing good basketball the last few weeks. The Panthers have won five straight games, including back to back comfortable wins on the road against quality opponents in Northwestern and NC State.

Vandy has losses at home this season already to Memphis and Southern Miss. Their most impressive win was an overtime win against Temple. If Pitt plays up to par with how they have in their last five games, the Panthers should cover comfortably here.

BET: Pittsburgh +3.5 (-110) at DraftKings Sportsbook

Best College Basketball Parlay Today

There are numerous different ways you can wager on College Basketball games in 2022, such as the moneyline, spread, total, player and team props, and, of course, parlays. While we normally suggest taking our picks on their own, we also really love parlays! With that said, check out the fat payout you can get by throwing all of our best bets together tonight. 

🔥 Penn State -3.5
🔥 Florida +4.5
🔥 Pittsburgh +3.5

*All odds and lines correct at time of publishing