NBA- More Betting
Cavaliers vs. Clippers: Betting Picks, Predictions and Odds - Wed Oct 27, 2021

The Los Angeles Clippers host the Cleveland Cavaliers in NBA action at Staples Center on Wednesday, beginning at 10:30 PM EDT.
Dimers' top betting picks for Cavaliers vs. Clippers, plus our score prediction and best odds, are featured below.
Who will win Cavaliers vs. Clippers?
Using advanced machine learning and data, Dimers.com has simulated Wednesday's Cavaliers-Clippers game 10,000 times.
Dimers' leading predictive analytics model, DimersBOT, gives the Clippers a 75% chance of defeating the Cavaliers.
MORE: Cavaliers vs. Clippers simulated 10,000 times
Cavaliers vs. Clippers Betting Preview
The Clippers are -8 favorites against the Cavaliers, with -110 at BetMGM the best odds available.
For the underdog Cavaliers (+8) to cover the spread, BetMGM also has the best odds on offer at -110.
DraftKings Sportsbook has the best moneyline odds for the Clippers at -350. That means you can risk $350 to win $100, for a total payout of $450, if they get the W.
Meanwhile, FanDuel Sportsbook has the best moneyline odds for the Cavaliers at +300, where you can bet $100 to profit $300, earning a total payout of $400, if they win.
The Over/Under for total points scored sits at 219.5 with BetMGM, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.
As always, check out all the legal sportbooks that are available in your state for the best NBA odds and lines.
According to DimersBOT, the Cavaliers (+8) are a 53% chance of covering the spread, while the 219.5-point Over/Under is considered an equal 50-50 chance of hitting.
Best bets for Cavaliers vs. Clippers:
- Spread: Cavaliers +8 at -110 with BetMGM (53% probability)
- Moneyline: Cavaliers Win at +300 with FanDuel Sportsbook (0.3% edge)
- Over/Under: Over 219.5 at -110 with BetMGM (50% probability)
While the Clippers are more likely to win the game, according to DimersBOT, betting on the Cavaliers moneyline is the best option because of the 0.3% edge found when comparing our data-led probabilities to the sportsbooks' odds.
Taking advantage of the edges published on Dimers is one of the keys to achieving long-term profitability.
MORE: Predictions and best bets for every NBA matchup
Cavaliers vs. Clippers Predicted Score
Dimers.com's predicted score for Cleveland vs. LA Clippers at Staples Center on Wednesday has the Clippers winning 113-105.
Dimers has full betting coverage of Wednesday's Cavaliers-Clippers matchup, including pre-game predictions, top betting picks, live win probabilities, and play-by-play commentary.
Don't forget, DimersBOT updates regularly, so keep checking this page for any changes ahead of Cavaliers vs. Clippers on Wednesday October 27, 2021.
Cavaliers vs. Clippers 2021 Game Info
When do the Clippers play the Cavaliers?
- Date: Wednesday October 27, 2021
- Time: 10:30 PM EDT
- Venue: Staples Center
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