Brewers vs. Reds Prediction and Odds - Sep 22, 2022

The Cincinnati Reds and Milwaukee Brewers lock horns in MLB at Great American Ball Park on Thursday, starting at 6:40PM ET.

Hunter Greene (4-12, 4.97 ERA) will start for the Reds, up against Brandon Woodruff (11-4, 3.26 ERA) for the Brewers.

Dimers' free betting picks for Brewers vs. Reds, plus game predictions and betting odds, are detailed in this article.


Who will win Brewers vs. Reds?

Based on cutting-edge computer power and data, has simulated Thursday's Brewers-Reds MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Brewers a 57% chance of defeating the Reds.

More: Free Betting Analysis for Brewers vs. Reds

Brewers vs. Reds Game Odds

  • Run Line: Reds +1.5 (-114), Brewers -1.5 (+100)
  • Moneyline: Reds +148, Brewers -164
  • Total: Over/Under 7.5 (-115/+100)

Run Line, Moneyline and Over/Under

The Reds are +1.5 underdogs against the Brewers, with -114 at FanDuel Sportsbook the best odds currently available.

For the favored Brewers (-1.5) to cover the run line, BetMGM has the best odds currently on offer at +100.

FanDuel Sportsbook currently has the best moneyline odds for the Reds at +148, which means you can bet $100 to profit $148, earning a total payout of $248, if they win.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Brewers at -164, where you can risk $164 to win $100, for a total payout of $264, if they come out on top.

The Over/Under for total runs scored is set at 7.5 with BetMGM, which currently has the best odds for the Over at -115, while DraftKings Sportsbook currently has the best odds for the Under at +100.

As always, check out all of the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Reds (+1.5) are a 57% chance of covering the run line, while the 7.5-run Over/Under is a 54% chance of going Over.

More: Best Free Bet Tracking Tool

Best Bets for Brewers vs. Reds


Dimers' best bets are based on detailed simulations and betting intelligence to help you make better investments with the legal sportsbooks in America.

While the Brewers are more likely to win the game, according to DimersBOT, taking the Reds moneyline is the best option due to the 2.8% edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen on is crucial to achieving long-term profitability.

Brewers vs. Reds Probabilities

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Dimers has full coverage of Thursday's Brewers-Reds matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so check this page for any changes to our betting insights before Brewers vs. Reds on Thursday September 22, 2022.


Brewers vs. Reds 2022 Game Info

Thursday's action between the Reds and Brewers at Great American Ball Park is scheduled to begin at 6:40PM ET.

  • Who: Milwaukee Brewers vs. Cincinnati Reds
  • Date: Thursday September 22, 2022
  • Time: 6:40PM ET / 3:40PM PT
  • Venue: Great American Ball Park

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