Blue Jays vs. Phillies Prediction and Odds - Sep 21, 2022

The Philadelphia Phillies square off with the Toronto Blue Jays in MLB action at Citizens Bank Park on Wednesday, starting at 6:45PM ET.

Zack Wheeler (11-7, 3.06 ERA) will be on the bump for the Phillies, up against Kevin Gausman (12-10, 3.45 ERA) for the Blue Jays.

Dimers' top betting picks for Blue Jays vs. Phillies, plus game predictions and best odds, are featured below.

Who will win Blue Jays vs. Phillies?

Using high-tech machine learning and data, Dimers.com has simulated Wednesday's Blue Jays-Phillies MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Phillies a 52% chance of beating the Blue Jays.

More: Free Betting Analysis for Blue Jays vs. Phillies

Blue Jays vs. Phillies Odds

• Run Line: Phillies +1.5 (-180), Blue Jays -1.5 (+155)
• Moneyline: Phillies -108, Blue Jays -105
• Total: Over/Under 8 (-120/+100)

Run Line, Moneyline and Over/Under

The Phillies are listed as +1.5 underdogs versus the Blue Jays, with -180 at DraftKings Sportsbook the best odds currently available.

For the favored Blue Jays (-1.5) to cover the run line, DraftKings Sportsbook also has the best odds currently on offer at +155.

In a sign of how close this game is expected to be, both the Phillies and Blue Jays are currently at minus-money betting odds on the moneyline.

FanDuel Sportsbook currently has the best moneyline odds for the Phillies at -108, which means you can risk $108 to win $100, for a total payout of $208, if they get the W.

Elsewhere, BetMGM currently has the best moneyline odds for the Blue Jays at -105, where you can risk $105 to win $100, for a total payout of $205, if they come out on top.

The Over/Under sits at 8 with BetMGM, which currently has the best odds for the Over at -120, as well as the best odds for the Under at +100.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Phillies (+1.5) are a 64% chance of covering the run line, while the 8-run Over/Under is a 57% chance of going Over.

More: Best Free Bet Tracker

Best Bets for Blue Jays vs. Phillies

• Run Line: Phillies +1.5 @ -180 via DraftKings Sportsbook (64% probability)
• Moneyline: Phillies @ -108 via FanDuel Sportsbook (52% probability)
• Total: Over 8 @ -120 via BetMGM (57% probability)

Our best bets are based on detailed modeling and wagering expertise to help you make more informed investments with the legal sportsbooks in America.

Blue Jays vs. Phillies Probabilities

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Dimers has full betting coverage of Wednesday's Blue Jays-Phillies matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates often, so keep an eye on this article for the latest betting insights ahead of Blue Jays vs. Phillies on Wednesday September 21, 2022.

Blue Jays vs. Phillies 2022 Game Info

Wednesday's action between the Phillies and Blue Jays at Citizens Bank Park is scheduled to start at 6:45PM ET.

• Who: Toronto Blue Jays vs. Philadelphia Phillies
• Date: Wednesday September 21, 2022
• Time: 6:45PM ET / 3:45PM PT
• Venue: Citizens Bank Park

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What other MLB games are on today?

Now you've got the 411 on Blue Jays vs. Phillies, get the latest betting predictions for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, and our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds available.