Best MLB Betting Picks and Parlay - Sunday, September 25, 2022

The MLB season continues to travel towards the postseason as we go looking for our best bets of the day.

It's Sunday, September 25, 2022, and, as always, we've simulated all of the day's MLB games 10,000 times each to determine where the value lies for sports bettors across the United States.

With our MLB best bets, probabilities, and odds featured each and every day, check out our best betting picks for Sunday's MLB games below.

Today's best MLB prop bets and odds are proudly brought to you by DraftKings Sportsbook.

Not with DraftKings yet? Well, sign up now and you'll get access to the best new customer MLB offer available. It's a bet $5 and get $100 no matter what offer, so simply click ➡️ here ⬅️, or tap the yellow button below.

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Best MLB Bets Today

Blue Jays vs. Rays, 1:10PM ET

Shane McClanahan (12-6, 2.36 ERA) gets the start for the Rays today and as a result we see the equal lowest run total this year in 6.5. It's true that McClanahan has been an elite level pitcher this season who hasn't given up a run in his last two starts, but he will surely be tested against Toronto - the 5th best run offense in the MLB by runs scored per game. On that fact as well, while Tampa haven't exactly been an elite offense, they have been finding a rhythm over the last couple of weeks, averaging close to 5 runs per game in their own right. This is a total than can be attacked today.

BET: Total runs OVER 6.5 (-115). Place this bet with DraftKings Sportsbook ➡️ here ⬅️.

⚾️ Blue Jays vs. Rays Predictions
📈 Betting preview: Blue Jays vs. Rays

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Angels vs. Twins, 2:10PM ET

Minnesota have been in free fall over the past two weeks but they were able to arrest the slide last night with a 8-4 win over the Halos for what is just their second victory from their past 10 games. However with their season well and truly done with hopes of an AL Central title dashed because of their recent form, we could see another letdown spot against the Angels here. Starting Twins ace Dylan Bundy (8-7, 4.78 ERA) is woefully out of form in recent times, notching a 8.78 ERA without a recorded win in each of his last three games. This is a matchup between two teams just running out the clock on the year, but the Angels have just a little more momentum overall to make a good fist of things here.

BET: Angels moneyline (-104) with DraftKings Sportsbook. Click ➡️ here ⬅️ to place your bet.

⚾️ Angels vs. Twins Predictions
📈 Betting preview: Angels vs. Twins

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Guardians vs. Rangers, 2:35PM ET

1 is the magic number now for the Guardians, meaning a win today will seal postseason baseball for a team that was +10000 to win the World Series in April. While a world championship is probably still a little premature for this young squad, we should see a motivated Guardians team out there today, with a favorable pitching matchup and Texas' Cole Ragans (0-2, 5.40 ERA). Ragans has been wayward at times through the first six starts in his career and should act as nothing other than a sacrificial lamb.

BET: Guardians moneyline (-138). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.

⚾️ Guardians vs. Rangers Predictions
📈 Betting preview: Guardians vs. Rangers

Your game not here? Find out who we're betting on for every baseball game on Sunday via our MLB Bet Hub, where we deliver you MLB predictions and suggested bets, or check out the MLB Betting News section.

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Best MLB Parlay Today

There are numerous different ways you can wager on MLB games in 2022, such as the moneyline, run line, total, player and team props (strikeouts, RBIs, and home runs), and, of course, parlays. Given the high-risk, high reward nature of parlays, we're going to use the DraftKings Bet $5, win $100 no matter what promo to guarantee a big cash.

Here's how to do it.

First, create your DraftKings account ➡️ here ⬅️, then make your first deposit of at least $5. Use that $5 to place a parlay using the below plays. If the parlay hits, you get yourself a nice payout, plus that $100 bonus. If it doesn't hit, well you've still got $100 free from DraftKings just for betting on MLB. Win-win!

🔥 Blue Jays-Rays o6.5 runs
🔥 Angels ML
🔥 Guardians ML

MORE: Sunday's MLB Props and Parlay

*All odds and lines correct at time of publishing