Astros vs. Yankees Computer Picks, MLB Odds and Betting Lines for October 23, 2022

The Yankees are staring down an ALCS sweep as they meet up with the Astros for Game 4 at Yankee Stadium tonight. Will Houston book their ticket to the World Series?

It's Sunday, October 23, 2022, and, as always, we've simulated all of the day's MLB games 10,000 times each to determine where the value lies for sports bettors across the United States.

With our MLB best bets, probabilities, and odds featured each and every day, check out our best betting picks for Wednesday's MLB games below.

Today's best MLB prop bets and odds are proudly brought to you by DraftKings Sportsbook.

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Best MLB Bet Today

Astros vs. Yankees, 7:07PM ET

New York never got close in last night's Game 3 as the Astros ran rampant with a 5-0 win in an indication that not only are the 'Stros the better team, they're also the best equipped to deal with the pressure that comes with postseason baseball.

Lance McCullers Jr will be the man trusted with the ball for Houston to try and close this thing out, and bettors should expect to see a tight performance with a lot of strikeouts with the ace averaging 7.4 Ks across his last five starts. Having a pitcher with such a high strikeout rate could be a major factor in deciding this game because that's just about all these Yankees hitters have been doing this series - they've struck out in 50% of all outs through the opening three games. Not getting the ball into play is kind of a problem.

The Astros have looked far too polished so far. They've been here before - many times - and they are playing to their strengths in breaking this New York team with stifling defense. With Nestor Cortes starting on the mound for the Yanks - a pitcher who has a 8.04 career ERA against Houston from 6 career appearances - the advantage lies well and truly with last year's AL champions.

BET: Astros Moneyline (+104). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.

Best MLB Prop Today

As mentioned above, the Yankees are striking out a ton, and starting Astros pitcher Lance McCullers strikes batters out a ton. The line set by the 'books sits at 5.5 Ks, but if you dive into the Alternative Strikeout market, you'll get some nice plus odds on his recent 5-game average.

BET: Lance McCullers 7+ Strikeouts (+136). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.

⚾️ Astros vs. Yankees Predictions
✍🏼 Betting Preview: Astros vs. Yankees

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Best MLB Same Game Parlay Today

There are numerous different ways you can wager on MLB games in 2022, such as the moneyline, run line, total, player and team props (strikeouts, RBIs, and home runs), and, of course, parlays. Given the high-risk, high reward nature of parlays, we're going to use the DraftKings Bet $5, win $200 no matter what promo to guarantee a big cash.

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🔥 Astros ML
🔥 McCullers 7+ Strikeouts

*All odds and lines correct at time of publishing