Astros vs. Orioles Prediction and Odds - Sep 24, 2022

MLB action continues on Saturday at 7:05PM ET as the Houston Astros square off with the Baltimore Orioles at Oriole Park at Camden Yards.

Mike Baumann (1-3, 4.29 ERA) will start on the mound for the Orioles, while the Astros will counter with Framber Valdez (16-5, 2.57 ERA).

Dimers' top betting picks for Astros vs. Orioles, as well as game predictions and best odds, are detailed in this article.


Who will win Astros vs. Orioles?

Using state-of-the-art computer power and data, has simulated Saturday's Astros-Orioles MLB game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Astros a 64% chance of defeating the Orioles.

More: Astros vs. Orioles Simulated 10K Times

Astros vs. Orioles Current Odds

  • Run Line: Orioles +1.5 (+100), Astros -1.5 (-110)
  • Moneyline: Orioles +176, Astros -190
  • Total: Over/Under 7.5 (-104/-110)

Run Line, Moneyline and Over/Under

The Orioles are +1.5 underdogs versus the Astros, with +100 at Caesars Sportsbook the best odds currently available.

For the favored Astros (-1.5) to cover the run line, BetMGM has the best odds currently on the market at -110.

FanDuel Sportsbook currently has the best moneyline odds for the Orioles at +176, which means you can bet $100 to profit $176, earning a total payout of $276, if they win.

On the other hand, BetMGM currently has the best moneyline odds for the Astros at -190, where you can risk $190 to win $100, for a total payout of $290, if they come out on top.

The Over/Under for total runs scored sits at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -104, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 51% chance of covering the run line, while the Over/Under total of 7.5 runs is a 55% chance of going Over.

More: Free Prop Picks

Best Bets for Astros vs. Orioles


When you see a 🔥, that means you've found one of our best free picks of the day across all sports.

Dimers' best bets are based on world-class simulations and betting intelligence to serve you the best possible plays 24/7.

While the Astros are more likely to win the game, according to DimersBOT, betting on the Orioles moneyline is the best option due to the edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen here at Dimers is crucial to being a profitable sports bettor in the long run.

Astros vs. Orioles Prediction

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Dimers has full coverage of Saturday's Astros-Orioles matchup, including pregame predictions, free picks, and live scores.

Remember, DimersBOT updates often, so keep an eye on this article for the latest betting analysis ahead of Astros vs. Orioles on Saturday September 24, 2022.


Astros vs. Orioles 2022 Game Info

Saturday's game between the Orioles and Astros at Oriole Park at Camden Yards is scheduled to commence at 7:05PM ET.

  • Who: Houston Astros vs. Baltimore Orioles
  • Date: Saturday September 24, 2022
  • Time: 7:05PM ET / 4:05PM PT
  • Venue: Oriole Park at Camden Yards

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Want more MLB analysis like this?

To get more MLB betting predictions like you've just read for Astros vs. Orioles, all you've gotta do is visit Dimers' MLB Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can produce the best MLB betting previews available. We're able to do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds available.

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