Arizona Cardinals vs. Tampa Bay Buccaneers: Experts release early Week 13 predictions [2025]

The Arizona Cardinals and Tampa Bay Buccaneers will meet in Week 13 of the NFL season at Raymond James Stadium on Sunday, November 30, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Buccaneers as the most likely winner of this NFC clash.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Cardinals vs. Buccaneers predictions page.

Arizona vs. Tampa Bay early predictions

Leveraging trusted machine learning and analysis, we have simulated the Cardinals vs. Bucs game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Cardinals 41%, Buccaneers 59%
• Predicted final score: Cardinals 21-23 Buccaneers
• Spread: Cardinals (+3) 58%, Buccaneers (-3) 42%
• Total points (44.5): Over 50%, Under 50%

As of November 24, 2025, these Cardinals-Buccaneers calculations and predictions reflect the latest data and insights available.

Cardinals vs. Bucs Week 13 details

The NFL Week 13 matchup between the Buccaneers and Cardinals at Raymond James Stadium is scheduled for November 30, 2025.

• Who: Arizona Cardinals vs. Tampa Bay Buccaneers
• Date: Sunday, November 30, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Raymond James Stadium

Cardinals vs. Bucs opening odds

We've researched the best betting odds across America for this Week 13 game, which are listed here:

• Spread: Cardinals +3 (-110), Buccaneers -3 (-105)
• Moneyline: Cardinals +135, Buccaneers -155
• Total: Over/Under 44.5 (-110/-105)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Buccaneers, with a 59% win probability, will likely beat the Cardinals in Week 13 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Cardinals vs. Buccaneers matchup, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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