Angels vs. Twins Prediction and Odds - Sep 23, 2022

MLB action continues on Friday at 8:10PM ET as the Los Angeles Angels square off with the Minnesota Twins at Target Field.

Louie Varland (0-1, 5.23 ERA) will start on the mound for the Twins, while the Angels are going with Shohei Ohtani (13-8, 2.43 ERA).

Dimers' top betting picks for Angels vs. Twins, as well as game predictions and betting odds, are detailed in this article.


Who will win Angels vs. Twins?

Using cutting-edge computer power and data, has simulated Friday's Angels-Twins MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Angels a 57% chance of winning against the Twins.

More: Full Betting Analysis for Angels vs. Twins

Angels vs. Twins Game Odds

  • Run Line: Twins +1.5 (-125), Angels -1.5 (+110)
  • Moneyline: Twins +152, Angels -164
  • Total: Over/Under 6.5 (-118/+100)

Run Line, Moneyline and Over/Under

The Twins are listed as +1.5 underdogs versus the Angels, with -125 at DraftKings Sportsbook the best odds currently available.

For the favored Angels (-1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at +110.

FanDuel Sportsbook currently has the best moneyline odds for the Twins at +152. That means you can bet $100 to profit $152, earning a total payout of $252, if they win.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Angels at -164, where you can risk $164 to win $100, for a total payout of $264, if they come out on top.

The Over/Under for total runs scored sits at 6.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -118, while BetMGM currently has the best odds for the Under at +100.

As always, make sure you check all of the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Twins (+1.5) are a 56% chance of covering the run line, while the Over/Under total of 6.5 runs is a 58% chance of going Over.

More: Best Prop Bets Today

Best Bets for Angels vs. Twins


Every time you see a 🔥, that means it's one of Dimers' best bets of the day across all major pro and college sports.

Dimers' best bets are based on detailed modeling and gambling intelligence to help you make smarter investments with the legal sportsbooks in America.

While the Angels are more likely to win the game, according to DimersBOT, taking the Twins moneyline is the best option because of the 3.8% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen on is crucial to being a profitable bettor in the long run.

Angels vs. Twins Prediction

Click or tap on See Matchup to reveal more.


Dimers has full coverage of Friday's Angels-Twins matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so check this page for any changes to our betting insights before Angels vs. Twins on Friday September 23, 2022.


Angels vs. Twins 2022 Game Info

Friday's game between the Twins and Angels at Target Field is scheduled to begin at 8:10PM ET.

  • Who: Los Angeles Angels vs. Minnesota Twins
  • Date: Friday September 23, 2022
  • Time: 8:10PM ET / 5:10PM PT
  • Venue: Target Field

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Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.

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