Blue Jays vs. Yankees prediction: Yankees favored to win Friday's MLB matchup [8/21/2026]
Get Toronto Blue Jays vs New York Yankees predictions for MLB Friday.

The New York Yankees and Toronto bluejays will lock horns in MLB action at Yankee Stadium on Friday, starting at 7:05 PM ET.
Cam Schlittler (10-6, 2.19 ERA) will be the starting pitcher for the Yankees, while the Blue Jays will counter with Mason Fluharty (5-1, 3.71 ERA).
Dimers' advanced MLB model projects the Yankees as the most likely winner in this Blue Jays vs. Yankees prediction.
This article offers further insights into Friday's matchup, including best bets and picks.
For more, dive into Cam Schlittler's pitching projections.
Blue Jays vs. Yankees prediction: Who will win and cover?
Our famous predictive model gives the Yankees a 60.5% chance of defeating the Blue Jays.
According to our model, the Blue Jays (+1.5) have a 57.0% chance of covering the run line, while the 7.5-run over/under has a 53.7% chance of going over.
Blue Jays vs. Yankees odds [8/21/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Blue Jays +1.5 (-120) / Yankees -1.5 (+117)
- Moneyline: Blue Jays +186, Yankees -186
All odds are correct at the time of publication and are subject to change.
Blue Jays vs. Yankees picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Blue Jays +1.5 @ -120 via DraftKings
- Moneyline: Blue Jays @ +186 via Novig
- Total: Over 7.5 @ +125 via Novig
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Blue Jays vs. Yankees game-day updates and essential details
Friday's MLB game between the Yankees and Blue Jays at Yankee Stadium is scheduled to begin at 7:05 PM ET.
- Who: Toronto Blue Jays vs. New York Yankees
- Date: Friday, August 21, 2026
- Time: 7:05 PM ET/4:05PM PT
- Venue: Yankee Stadium
Conclusion
We predict the Yankees, with a 60.5% win probability, will likely beat the Blue Jays in Friday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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