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Read Article Twins vs. Cubs prediction: Why Cubs are favored to win Friday's MLB matchup [7/17/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Minnesota Twins vs Chicago Cubs predictions for MLB Friday.
The Chicago Cubs and Minnesota Twins will lock horns in MLB action at Wrigley Field on Friday, starting at 8:05 PM ET.
The Cubs will start Colin Rea (7-5, 4.75 ERA), pitting him against Bailey Ober (6-3, 4.40 ERA) for the Twins.
Based on updated simulations, Dimers' advanced MLB model predicts the Cubs as the most likely winner of the Twins vs. Cubs game.
This article offers a closer look at Friday's matchup, including best bets and picks.
Twins vs. Cubs prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the outcome of Friday's MLB matchup between the Twins and Cubs, forming part of our MLB predictions coverage.
Our famous predictive model gives the Cubs a 57.4% chance of beating the Twins.
According to our model, the Twins (+1.5) have a 58.7% chance of covering the run line, while the 11-run over/under has a 50.3% chance of going over,.
Twins vs. Cubs odds [7/17/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Twins | Cubs |
|---|---|---|
| Run Line | +1.5 (-144) | -1.5 (+141) |
| Moneyline | +135 | -138 |
| Total | o11 (-107) | u11 (+105) |
All odds are correct at the time of publication and are subject to change.
Twins vs. Cubs picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Cubs -1.5 | +141 |
| Moneyline | Twins | +135 |
| Total | Under 11 | +105 |
According to our MLB best bets, the top play to make on this game is Under 11 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Twins vs. Cubs game-day updates and essential details
Friday's MLB game between the Cubs and Twins at Wrigley Field is scheduled to commence at 8:05 PM ET.
- Who: Minnesota Twins vs. Chicago Cubs
- Date: Friday, July 17, 2026
- Time: 8:05 PM ET/5:05PM PT
- Venue: Wrigley Field
Conclusion
We predict the Cubs, with a 57.4% win probability, will likely beat the Twins in Friday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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