Brewers vs. Padres prediction: San Diego favored to win Monday's MLB matchup [8/10/2026]

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Written by Dave Garofolo

Get Milwaukee Brewers vs San Diego Padres predictions for MLB Monday.

Milwaukee Brewers-San Diego Padres Predictions and Game Preview.
Milwaukee Brewers vs. San Diego Padres MLB prediction for Monday, August 10, 2026.

The San Diego Padres will take on the Milwaukee Brewers, in what is expected to be a close MLB game, at Petco Park on Monday, beginning at 9:40 PM ET.

Casey Mize (4-7, 3.40 ERA) will start on the mound for the Padres, up against Logan Henderson (6-1, 2.70 ERA) for the Brewers.

Dimers' proven MLB model gives the Padres a slight edge with a 50.6% win probability over the Brewers.

This article offers a closer look at Monday's Brewers vs. Padres matchup, including best bets and picks.

Brewers vs. Padres prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Monday's MLB game between the Brewers and Padres, forming part of our MLB predictions coverage.

Our leading predictive model currently gives the Padres a 50.6% chance of defeating the Brewers.

According to our model, the Padres (+1.5) have a 64.0% chance of covering the run line, while the 7-run over/under has a 56.9% chance of going over,.

 

Brewers vs. Padres odds [8/10/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

  • Run Line: Brewers -1.5 (+160) / Padres +1.5 (-163)
  • Moneyline: Brewers -112, Padres +111

All odds are correct at the time of publication and are subject to change.

Brewers vs. Padres picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

  • Run line: Padres +1.5 @ -163 via DraftKings
  • Moneyline: Padres @ +111 via Novig
  • Total: Over 7 @ -105 via DraftKings

According to our best MLB bets, the top play to make on this game is Over 7 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Brewers vs. Padres game-day updates and essential details

Monday's MLB matchup between the Padres and Brewers at Petco Park is scheduled to begin at 9:40 PM ET.

Conclusion

We predict the Padres, with a 50.6% win probability, will likely beat the Brewers in Monday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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