Sep 2, 2026
Marlins vs. Royals prediction: Kansas City favored to win Wednesday's MLB matchup [9/2/2026]
Read Article Brewers vs. Cubs prediction: Why Milwaukee is favored to win Wednesday's MLB matchup [9/2/2026]
Updated: | First published:
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Written by Dave Garofolo, Content Producer
Dimers' simulation model projects a 53.9% win probability for the Brewers at Wrigley Field.
The Chicago Cubs will square off with the Milwaukee Brewers, in what is expected to be a tight MLB game, at Wrigley Field on Wednesday, starting at 7:40 PM ET.
David Peterson (7-7, 5.11 ERA) will be the starting pitcher for the Cubs, up against Jacob Misiorowski (14-5, 1.73 ERA) for the Brewers.
Dimers' proven MLB model gives the Brewers a slight edge with a 53.9% win probability over the Cubs.
This article offers a complete Brewers vs. Cubs prediction, including best bets and picks.
For more, dive into Jacob Misiorowski's projected pitching stats.
Brewers vs. Cubs prediction and odds
Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB game between the Brewers and Cubs, forming part of our MLB predictions coverage.
Our leading predictive model gives the Brewers a 53.9% chance of defeating the Cubs.
According to our model, the Cubs (+1.5) have a 58.5% chance of covering the run line, while the 8.5-run over/under has a 53.7% chance of going over.
Latest betting odds
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Brewers -1.5 (+113) / Cubs +1.5 (-111)
- Moneyline: Brewers -147, Cubs +144
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Cubs +1.5 @ 53¢ via Novig
- Moneyline: Cubs @ 41¢ via Novig
- Total: Over 8.5 @ 48¢ via Polymarket
According to our MLB best bets, the top play to make on this game is Cubs +1.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Wednesday's MLB matchup between the Cubs and Brewers at Wrigley Field is scheduled to commence at 7:40 PM ET.
- Who: Milwaukee Brewers vs. Chicago Cubs
- Date: Wednesday, September 2, 2026
- Time: 7:40 PM ET/4:40PM PT
- Venue: Wrigley Field
Conclusion
We predict the Brewers, with a 53.9% win probability, will likely beat the Cubs in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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