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Read Article Astros vs. Yankees prediction: Yankees favored to win Wednesday's MLB matchup [8/26/2026]
Updated: | First published:
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Written by Jason Bevilacqua, Head of Content and Communities
Get Houston Astros vs New York Yankees predictions for MLB Wednesday.
The New York Yankees will square off with the Houston Astros, in what is expected to be a tight MLB game, at Yankee Stadium on Wednesday, beginning at 7:05 PM ET.
The Yankees will start Elmer Rodríguez (0-2, 4.76 ERA), while the Astros are going with Peter Lambert (8-7, 3.68 ERA).
Dimers' advanced MLB model gives the Yankees a slight edge with a 52.1% win probability over the Astros.
This article offers a complete Astros vs. Yankees prediction, including best bets and picks.
Astros vs. Yankees prediction: Who will win and cover?
Using innovative machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB game between the Astros and Yankees, forming part of our MLB predictions coverage.
Our independent predictive model gives the Yankees a 52.1% chance of defeating the Astros.
According to our model, the Astros (+1.5) have a 63.5% chance of covering the run line, while the 8.5-run over/under has a 57.2% chance of going over.
Astros vs. Yankees odds [8/26/2026]
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: Astros +1.5 (-178) / Yankees -1.5 (+170)
- Moneyline: Astros +125, Yankees -115
All odds are correct at the time of publication and are subject to change.
Astros vs. Yankees picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Yankees -1.5 @ +170 via DraftKings
- Moneyline: Astros @ +125 via Bet365
- Total: Over 8.5 @ -113 via Polymarket
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Astros vs. Yankees game-day updates and essential details
Wednesday's MLB game between the Yankees and Astros at Yankee Stadium is scheduled to start at 7:05 PM ET.
- Who: Houston Astros vs. New York Yankees
- Date: Wednesday, August 26, 2026
- Time: 7:05 PM ET/4:05PM PT
- Venue: Yankee Stadium
Conclusion
We predict the Yankees, with a 52.1% win probability, will likely beat the Astros in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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