Sep 13, 2026
Royals vs. Red Sox prediction: Boston favored to win Sunday's MLB matchup [9/13/2026]
Read Article White Sox vs. Cardinals prediction: White Sox favored to win Sunday's MLB matchup [9/13/2026]
Updated: | First published:
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Written by Dave Garofolo, Content Producer
Dimers' simulation model projects a 52.1% win probability for the White Sox at Busch Stadium.
MLB action continues on Sunday at 2:15 PM ET as the Chicago White Sox square off with the St. Louis Cardinals at Busch Stadium.
The Cardinals will start Michael McGreevy (6-9, 3.92 ERA), while the White Sox have opted for Sean Burke (8-7, 3.58 ERA).
Dimers' advanced MLB model gives the White Sox a slight edge with a 52.1% win probability over the Cardinals.
This article offers a complete White Sox vs. Cardinals prediction, including best bets and picks.
White Sox vs. Cardinals prediction and odds
Using powerful machine learning and data, we have re-simulated the result of Sunday's MLB matchup between the White Sox and Cardinals, forming part of our MLB predictions coverage.
Our independent predictive model gives the White Sox a 52.1% chance of beating the Cardinals. According to our model, the Cardinals (+1.5) have a 61.2% chance of covering the run line, while the 7.5-run over/under has a 56.2% chance of going over.
Latest betting odds
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: White Sox -1.5 (+138) / Cardinals +1.5 (-145)
- Moneyline: White Sox -117, Cardinals +120
- Total: Over/Under 7.5 (-117/+115)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Cardinals +1.5 @ -145 via Caesars
- Moneyline: Cardinals @ +120 via bet365
- Total: Over 7.5 @ 54¢ via Polymarket
According to our MLB best bets, the top play to make on this game is Cardinals to win.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Sunday's MLB matchup between the Cardinals and White Sox at Busch Stadium is scheduled to commence at 2:15 PM ET.
- Who: Chicago White Sox vs. St. Louis Cardinals
- Date: Sunday, September 13, 2026
- Time: 2:15 PM ET/11:15AM PT
- Venue: Busch Stadium
Conclusion
We predict the White Sox, with a 52.1% win probability, will likely beat the Cardinals in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
This article's predictions and probabilities are generated by Dimers' proprietary MLB prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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