Aug 18, 2026
Giants vs. Guardians prediction: Why Cleveland is favored to win Tuesday's MLB matchup [8/18/2026]
Read Article White Sox vs. Cubs prediction: Why Cubs are favored to win Tuesday's MLB matchup [8/18/2026]
Updated: | First published:
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Written by Dave Garofolo, Content Producer
Get Chicago White Sox vs Chicago Cubs predictions for MLB Tuesday.
The Chicago Cubs will face the Chicago White Sox in MLB action at Wrigley Field on Tuesday, starting at 8:05 PM ET.
The Cubs will start Kevin Gausman (6-11, 4.53 ERA), while the White Sox have opted for Bryan Hudson (3-4, 3.14 ERA).
Dimers' proven MLB model projects the Cubs as the most likely winner in this White Sox vs. Cubs prediction.
This article offers further insights into Tuesday's matchup, including best bets and picks.
White Sox vs. Cubs prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Tuesday's MLB game between the White Sox and Cubs, forming part of our MLB predictions coverage.
Our famous predictive model gives the Cubs a 61.5% chance of defeating the White Sox.
According to our model, the White Sox (+1.5) have a 56.6% chance of covering the run line, while the over/under total of 8.5 runs has a 55.6% chance of going over,.
White Sox vs. Cubs odds [8/18/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: White Sox +1.5 (-135) / Cubs -1.5 (+133)
- Moneyline: White Sox +157, Cubs -160
All odds are correct at the time of publication and are subject to change.
White Sox vs. Cubs picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Cubs -1.5 @ +133 via DraftKings
- Moneyline: Cubs @ -160 via DraftKings
- Total: Over 8.5 @ -122 via Polymarket
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
White Sox vs. Cubs game-day updates and essential details
Tuesday's MLB action between the Cubs and White Sox at Wrigley Field is scheduled to commence at 8:05 PM ET.
- Who: Chicago White Sox vs. Chicago Cubs
- Date: Tuesday, August 18, 2026
- Time: 8:05 PM ET/5:05PM PT
- Venue: Wrigley Field
Conclusion
We predict the Cubs, with a 61.5% win probability, will likely beat the White Sox in Tuesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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