Cubs vs. Nationals prediction: Why Cubs are favored to win Wednesday's MLB matchup [8/12/2026]
Get Chicago Cubs vs Washington Nationals predictions for MLB Wednesday.
The Washington Nationals will take on the Chicago Cubs in MLB action at Nationals Park on Wednesday, beginning at 6:45 PM ET.
Jackson Kent (0-0, 0.00 ERA) will start for the Nationals, while the Cubs will counter with David Peterson (6-7, 5.35 ERA).
Dimers' advanced MLB model projects the Cubs as the most likely winner in this Cubs vs. Nationals prediction.
This article offers an expanded analysis of Wednesday's matchup, including best bets and picks.
Cubs vs. Nationals prediction: Who will win and cover?
Our independent predictive model currently gives the Cubs a 59.9% chance of beating the Nationals.
According to our model, the Nationals (+1.5) have a 53.4% chance of covering the run line, while the over/under total of 9.5 runs has a 50.7% chance of going over,.
Cubs vs. Nationals odds [8/12/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Cubs -1.5 (+105) / Nationals +1.5 (-106)
- Moneyline: Cubs -150, Nationals +150
All odds are correct at the time of publication and are subject to change.
Cubs vs. Nationals picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Nationals +1.5 @ -106 via DraftKings
- Moneyline: Nationals @ +150 via Novig
- Total: Over 9.5 @ +104 via Novig
According to our MLB best bets, the top play to make on this game is Nationals +1.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Cubs vs. Nationals game-day updates and essential details
Wednesday's MLB matchup between the Nationals and Cubs at Nationals Park is scheduled to start at 6:45 PM ET.
- Who: Chicago Cubs vs. Washington Nationals
- Date: Wednesday, August 12, 2026
- Time: 6:45 PM ET/3:45PM PT
- Venue: Nationals Park
Conclusion
We predict the Cubs, with a 59.9% win probability, will likely beat the Nationals in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
