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Read Article Red Sox vs. Yankees prediction: Yankees favored to win Friday's MLB matchup [6/5/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Boston Red Sox vs New York Yankees predictions for MLB Friday.
The New York Yankees will take on the Boston Red Sox in MLB action at Yankee Stadium on Friday, starting at 7:05 PM ET.
Ryan Weathers (2-3, 3.52 ERA) will get the ball for the Yankees, pitting him against Sonny Gray (6-1, 3.06 ERA) for the Red Sox.
Based on the latest simulation results, Dimers' proven MLB model predicts the Yankees as the most likely winner of the Red Sox vs. Yankees game.
This article offers a closer look at Friday's matchup, including best bets and picks.
Red Sox vs. Yankees prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of Friday's MLB game between the Red Sox and Yankees, forming part of our MLB predictions coverage.
Our leading predictive model currently gives the Yankees a 56.9% chance of beating the Red Sox.
According to our model, the Red Sox (+1.5) have a 60.0% chance of covering the run line, while the 8-run over/under has a 56.8% chance of going over.
Red Sox vs. Yankees odds [6/5/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Red Sox | Yankees |
|---|---|---|
| Run Line | +1.5 (-166) | -1.5 (+145) |
| Moneyline | +122 | -144 |
| Total | o8 (-114) | u8 (-105) |
All odds are correct at the time of publication and are subject to change.
Red Sox vs. Yankees picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Yankees -1.5 | +145 |
| Moneyline | Red Sox | +122 |
| Total | Over 8 | -114 |
According to our MLB best bets, the top play to make on this game is Over 8 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Red Sox vs. Yankees game-day updates and essential details
Friday's MLB game between the Yankees and Red Sox at Yankee Stadium is scheduled to commence at 7:05 PM ET.
- Who: Boston Red Sox vs. New York Yankees
- Date: Friday, June 5, 2026
- Time: 7:05 PM ET/4:05PM PT
- Venue: Yankee Stadium
Conclusion
We predict the Yankees, with a 56.9% win probability, will likely beat the Red Sox in Friday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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