Diamondbacks vs. Red Sox prediction: Boston favored to win Wednesday's MLB matchup [8/19/2026]
Get Arizona Diamondbacks vs Boston Red Sox predictions for MLB Wednesday.

MLB action continues on Wednesday at 4:10 PM ET as the Arizona Diamondbacks square off with the Boston Red Sox at Fenway Park.
Payton Tolle (8-6, 2.97 ERA) will start on the mound for the Red Sox, while the Diamondbacks will counter with Brandon Pfaadt (7-1, 3.11 ERA).
Dimers' proven MLB model gives the Red Sox a slight edge with a 54.9% win probability over the Diamondbacks.
This article offers a complete Diamondbacks vs. Red Sox prediction, including best bets and picks.
Diamondbacks vs. Red Sox prediction: Who will win and cover?
Our famous predictive model currently gives the Red Sox a 54.9% chance of defeating the Diamondbacks.
According to our model, the Diamondbacks (+1.5) have a 61.8% chance of covering the run line, while the 8.5-run over/under has a 55.3% chance of going over,.
Diamondbacks vs. Red Sox odds [8/19/2026]
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: Diamondbacks +1.5 (-156) / Red Sox -1.5 (+155)
- Moneyline: Diamondbacks +138, Red Sox -135
All odds are correct at the time of publication and are subject to change.
Diamondbacks vs. Red Sox picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Diamondbacks +1.5 @ -156 via DraftKings
- Moneyline: Diamondbacks @ +138 via Polymarket
- Total: Over 8.5 @ +113 via Polymarket
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Diamondbacks vs. Red Sox game-day updates and essential details
Wednesday's MLB game between the Red Sox and Diamondbacks at Fenway Park is scheduled to commence at 4:10 PM ET.
- Who: Arizona Diamondbacks vs. Boston Red Sox
- Date: Wednesday, August 19, 2026
- Time: 4:10 PM ET/1:10PM PT
- Venue: Fenway Park
Conclusion
We predict the Red Sox, with a 54.9% win probability, will likely beat the Diamondbacks in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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