Aug 29, 2026
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Read Article San Jose State vs. Southern California prediction: Southern California favored to win in college football Week 0 [2026]
Updated: | First published:
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Written by Mac Douglass, Senior Editor
Get San Jose State vs Southern California predictions for college football Saturday.
Southern California will take on San Jose State in Week 0 college football action at Los Angeles Memorial Coliseum on Saturday, commencing at 3:00 PM ET.
Dimers' proven college football model gives Southern California a slight edge with a 94.6% win probability over San Jose State.
This article offers a complete San Jose State vs. Southern California prediction, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons..
San Jose State vs. Southern California prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of San Jose State vs. Southern California, forming part of our college football predictions coverage.
Our independent predictive model gives Southern California a 94.6% chance of defeating San Jose State. Our predicted final score has Southern California winning 44-16.
According to our model, San Jose State (+38.5) has a 75.1% chance of covering the spread, while the 62-point over/under has a 54.1% chance of staying under.
San Jose State vs. Southern California odds
We have sourced the best college football odds in America for this game, which are listed here:
- Spread: San Jose State +38.5 (-109) / Southern California -38.5 (-110)
- Moneyline: San Jose State +3000, Southern California -10000
All odds are correct at the time of publication and are subject to change.
San Jose State vs. Southern California picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Spread: San Jose State +38.5 @ -109 via DraftKings
- Moneyline: San Jose State @ +3000 via Fanatics
- Total: Under 62 @ -115 via BetRivers
According to our best college football bets, the top play to make on this game is San Jose State +38.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
San Jose State vs. Southern California game-day updates and essential details
Saturday's college football game between Southern California and San Jose State at Los Angeles Memorial Coliseum is scheduled to begin at 3:00 PM ET.
- Who: San Jose State vs. Southern California
- Date: Saturday, August 29, 2026
- Time: 3:00 PM ET/12:00PM PT
- Venue: Los Angeles Memorial Coliseum
Conclusion
We predict Southern California, with a 94.6% win probability, will likely beat San Jose State in Saturday's college football matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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