Drake vs. Northern Iowa prediction favors Northern Iowa to win in college football Week 2 [2026]

Using innovative machine learning and data analysis, we have re-simulated the result of Drake vs. Northern Iowa, forming part of our college football predictions coverage.

Our famous predictive model currently gives Northern Iowa an 81.2% chance of defeating Drake. Our predicted final score has Northern Iowa winning 34-22. According to our model, Drake (+11.5) has a 50.1% chance of covering the spread, while the 58-point over/under has a 52.3% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Drake +11.5 (+100) / Northern Iowa -11.5 (-111)
• Moneyline: Drake +362, Northern Iowa -450
• Total: Over/Under 58 (-110/-110)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Drake +11.5 @ +100 via bet365
• Moneyline: Northern Iowa @ -450 via bet365
• Total: Under 58 @ -110 via bet365

According to our college football best bets, the top play to make on this game is Drake +11.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between Northern Iowa and Drake at UNI-Dome is scheduled to commence at 2:00 PM ET.

• Who: Drake vs. Northern Iowa
• Date: Saturday, September 12, 2026
• Time: 2:00 PM ET/11:00AM PT
• Venue: UNI-Dome

College football Week 2 promos

Make the most of Dimers' Drake vs. Northern Iowa predictions by exploring the Bet365 Sportsbook offer below:

Conclusion

We predict Northern Iowa, with an 81.2% win probability, will likely beat Drake in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.