Yankees vs. Red Sox Prediction, Picks and Odds

Our detailed prediction and analysis for the Yankees vs. Red Sox MLB game on April 22, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB sport icon
MLB
Yankees
4
1
Apr 22, 10:45PM Fenway Park
Red Sox
Apr 22, 10:45PM Fenway Park
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Bets
1 2 3 4 5 6 7 8 9 RHE
Yankees
3 0 1 0 0 0 0 0 0 4 6 0
Red Sox
0 0 0 0 0 0 0 0 1 1 5 0
Live Probabilities
Moneyline
Over / Under
Run Line
Yankees NYY
Win %
100%
0%
Red Sox BOS
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Caleb Durbin grounds out to shortstop, José Caballero to Paul Goldschmidt.
Quick Box Score
Hitting
Pitching
Yankees Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 P. Goldschmidt 1B4000002.0000.000
2 A. Judge RF2210020.5001.250
3 C. Bellinger LF4000001.0000.000
4 G. Stanton DH4120000.5001.500
5 R. McMahon 3B1000001.0000.000
6 T. Grisham CF2000001.0000.000
7 J. Chisholm 2B4000001.0000.000
8 J. Caballero SS3010001.3330.666
9 A. Wells C3000001.0000.000
Red Sox Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 C. Rafaela CF4000003.0000.000
2 W. Contreras 1B3000011.0000.250
3 W. Abreu RF4010000.2500.500
4 T. Story SS4110002.2500.500
5 A. Monasterio DH3000010.0000.250
6 J. Duran LF4031000.7502.000
7 C. Durbin 3B4000001.0000.000
8 C. Wong C3000001.0000.000
9 I. Kiner-Falefa 2B3000001.0000.000

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Yankees vs. Red Sox: Detailed Breakdown

Matchup Overview

  • Teams: Yankees vs. Red Sox
  • Date: Wednesday, April 22, 2026
  • Time: 6:45 PM ET
  • Venue: Fenway Park

Current Betting Odds

  • Spread: Yankees favored at -1.5
  • Total (Over/Under): 7.5
  • Moneyline Odds: Yankees -119, Red Sox +120

Dimers' Win Probabilities

  • Yankees: 52%
  • Red Sox: 48%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Yankees a win probability of 52%, while the Red Sox have a win probability of 48%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Yankees are more likely to beat the Red Sox in the MLB game at Fenway Park on Wednesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Yankees vs. Red Sox predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.