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Guardians vs. Twins Prediction, Picks and Odds

Our detailed prediction and analysis for the Guardians vs. Twins MLB game on May 21, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
Guardians
5
6
May 21, 5:10PM Target Field
Twins
May 21, 5:10PM Target Field
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Dimers Pro Best Bets
1 2 3 4 5 6 7 8 9 RHE
Guardians
1 0 0 1 0 0 0 0 3 5 8 0
Twins
1 1 0 2 0 0 0 1 1 6 12 0
Live Probabilities
Moneyline
Over / Under
Run Line
Guardians CLE
Win %
0%
100%
Twins MIN
Win Probability
Last At Bat
Outs
Kody Clemens doubles to deep center field. Jonah Bride to third. Ryan Fitzgerald scores.
Quick Box Score
Hitting
Pitching
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 S. Kwan LF40100010.250.500
2 A. Martínez CF41100010.250.500
3 J. Ramírez 3B41100000.250.750
4 K. Manzardo DH30110100.3331.167
5 C. Santana 1B42111020.251.250
6 N. Jones RF41110000.250.500
7 G. Arias SS400000100.000
8 B. Naylor C40120030.250.750
9 D. Schneemann 2B100000000.000
Twins Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 R. Jeffers C21100210.51.300
2 B. Lee SS400001200.200
3 R. Lewis DH40100110.250.900
4 R. Fitzgerald PR010000000.000
5 D. Keirsey LF110000000.000
6 J. Bride 3B50300010.61.200
7 K. Clemens 2B31220010.6672.334
8 H. Bader CF31120000.3330.583
9 W. Castro RF30110100.3331.167

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Guardians vs. Twins: Detailed Breakdown

Matchup Overview

  • Teams: Guardians vs. Twins
  • Date: Wednesday, May 21, 2025
  • Time: 1:10 PM ET
  • Venue: Target Field

Current Betting Odds

  • Spread: Twins favored at undefined
  • Total (Over/Under): 7.5
  • Moneyline Odds: Guardians +102, Twins -118

Dimers' Win Probabilities

  • Guardians: 43%
  • Twins: 57%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Guardians a win probability of 43%, while the Twins have a win probability of 57%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Twins are more likely to beat the Guardians in the MLB game at Target Field on Wednesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Guardians vs. Twins predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.

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