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Guardians vs. Reds Prediction, Picks and Odds

Our detailed prediction and analysis for the Guardians vs. Reds MLB game on May 16, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
Guardians
4
5
May 16, 9:10PM Great American Ball Park
Reds
May 16, 9:10PM Great American Ball Park
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Dimers Pro Best Bets
1 2 3 4 5 6 7 8 9 RHE
Guardians
0 0 0 2 1 0 0 1 0 4 5 1
Reds
0 4 1 0 0 0 0 0 X 5 11 0
Live Probabilities
Moneyline
Over / Under
Run Line
Guardians CLE
Win %
0%
100%
Reds CIN
Win Probability
Created with Highcharts 10.3.3Inning% ProbabilityGuardiansRedsE1E2E3E4E5E6E7E8F0255075100
Created with Highcharts 10.3.3Inning% ProbabilityGuardians -1.5Reds +1.5E1E2E3E4E5E6E7E8F0255075100
Created with Highcharts 10.3.3Inning% ProbabilityOver 9.5Under 9.5E1E2E3E4E5E6E7E8F0255075100
Last At Bat
Outs
Gabriel Arias strikes out swinging.
Quick Box Score
Hitting
Pitching
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 S. Kwan LF310001000.250
2 N. Jones CF400000200.000
3 J. Ramírez 3B41111000.251.250
4 K. Manzardo DH41100000.250.750
5 C. Santana 1B40120000.250.500
6 D. Schneemann 2B30100110.3330.833
7 G. Arias SS200001100.333
8 B. Naylor C31111010.3331.666
9 W. Brennan RF300000000.000
Reds Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 T. Friedl CF300001100.250
2 S. Espinal 3B40100000.250.500
3 E. De La Cruz SS30100110.3330.833
4 A. Hays LF41211000.51.750
5 G. Lux DH41200010.51.250
6 S. Steer 1B41100000.250.750
7 T. Stephenson C40100020.250.500
8 W. Benson RF41231000.51.750
9 M. McLain 2B41100020.250.500

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Guardians vs. Reds: Detailed Breakdown

Matchup Overview

  • Teams: Guardians vs. Reds
  • Date: Friday, May 16, 2025
  • Time: 5:10 PM ET
  • Venue: Great American Ball Park

Current Betting Odds

  • Spread: Guardians favored at -1.5
  • Total (Over/Under): 9.5
  • Moneyline Odds: Guardians -118, Reds +102

Dimers' Win Probabilities

  • Guardians: 51%
  • Reds: 49%

Dimers.com's predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Guardians a win probability of 51%, while the Reds have a win probability of 49%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Guardians are more likely to beat the Reds in the MLB game at Great American Ball Park on Friday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Guardians vs. Reds predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.

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