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Cardinals vs. Giants Prediction, Picks and Odds
Our detailed prediction and analysis for the Cardinals vs. Giants MLB game on September 22, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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FINAL
MLB
FINAL
MLB
6
5
Sep 23, 1:45AM Oracle Park
Sep 23, 1:45AM Oracle Park
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Bets
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | R | H | E | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cardinals | 0 | 0 | 1 | 1 | 4 | 0 | 0 | 0 | 0 | 6 | 10 | 1 |
Giants | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 5 | 7 | 2 |
Live Probabilities
Moneyline
Over / Under
Run Line
Win %
100%
0%
Win Probability
Last At Bat
Outs
Heliot Ramos grounds out to second base, José Fermín to Alec Burleson.
Quick Box Score
Hitting
Pitching
| No. | Player | Pos | AB | R | H | RBI | HR | BB | SO | AVG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | L. Nootbaar | LF | 4 | 1 | 1 | 0 | 0 | 1 | 2 | 0.25 | 0.650 |
| 2 | I. Herrera | DH | 3 | 1 | 1 | 2 | 1 | 1 | 0 | 0.333 | 1.933 |
| 3 | A. Burleson | 1B | 5 | 1 | 3 | 1 | 0 | 0 | 1 | 0.6 | 1.200 |
| 4 | N. Arenado | 3B | 5 | 1 | 1 | 0 | 0 | 0 | 3 | 0.2 | 0.600 |
| 5 | T. Saggese | SS | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 0.2 | 0.600 |
| 6 | P. Pagés | C | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 0.2 | 0.600 |
| 7 | J. Walker | RF | 3 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0.250 |
| 8 | J. Fermín | 2B | 4 | 1 | 2 | 1 | 0 | 0 | 1 | 0.5 | 1.500 |
| 9 | V. Scott | CF | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.000 |
| No. | Player | Pos | AB | R | H | RBI | HR | BB | SO | AVG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | H. Ramos | LF | 5 | 1 | 2 | 3 | 1 | 0 | 1 | 0.4 | 1.400 |
| 2 | R. Devers | 1B | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0.333 | 1.833 |
| 3 | W. Adames | SS | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.000 |
| 4 | M. Chapman | 3B | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0.25 | 0.500 |
| 5 | C. Koss | DH | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.000 |
| 6 | C. Schmitt | 2B | 4 | 1 | 1 | 0 | 0 | 0 | 1 | 0.25 | 0.500 |
| 7 | P. Bailey | C | 4 | 1 | 2 | 1 | 0 | 0 | 0 | 0.5 | 1.000 |
| 8 | J. Encarnación | RF | 4 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0.000 |
| 9 | W. Flores | PH | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0.000 |
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Cardinals vs. Giants: Detailed Breakdown
Matchup Overview
- Teams: Cardinals vs. Giants
- Date: Monday, September 22, 2025
- Time: 9:45 PM ET
- Venue: Oracle Park
Current Betting Odds
- Spread: Giants favored at -1.5
- Total (Over/Under): 7.5
- Moneyline Odds: Cardinals +130, Giants -140
Dimers' Win Probabilities
- Cardinals: 43%
- Giants: 57%
Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.
Our Prediction: Who Wins?
After extensive simulations, our model gives the Cardinals a win probability of 43%, while the Giants have a win probability of 57%. Discover the best spread, over/under, and moneyline odds for the game on this page.
Summary
According to our analysis, the Giants are more likely to beat the Cardinals in the MLB game at Oracle Park on Tuesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.
Our Cardinals vs. Giants predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.
For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.
