Brewers vs. Cardinals Prediction, Picks and Odds

Our detailed prediction and analysis for the Brewers vs. Cardinals MLB game on September 21, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB sport icon
MLB
Brewers
1
5
Sep 21, 6:15 PM Busch Stadium
Cardinals
Sep 21, 6:15 PM Busch Stadium
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Pro Bets
1 2 3 4 5 6 7 8 9 RHE
Brewers
0 0 0 0 1 0 0 0 0 1 7 0
Cardinals
0 0 2 2 0 0 0 1 X 5 3 0
Live Probabilities
Moneyline
Over / Under
Run Line
Brewers MIL
Win %
0%
100%
Cardinals STL
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Isaac Collins flies out to shallow left field to Nathan Church.
Quick Box Score
Hitting
Pitching
Brewers Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 J. Chourio RF400100300.000
2 I. Collins LF300002100.400
3 A. Vaughn 1B400000100.000
4 C. Yelich DH100000100.000
5 C. Durbin 3B200000000.500
6 A. Monasterio 2B40300000.751.500
7 D. Jansen C400000100.000
8 B. Turang PH100000000.000
9 J. Bauers PH000000001.000
Cardinals Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 T. Saggese SS400000000.000
2 I. Herrera DH22121100.52.750
3 A. Burleson 1B30100110.3330.833
4 N. Church LF000000000.000
5 J. Walker RF210001000.500
6 N. Gorman 3B310001100.250
7 J. Fermín 2B30130110.3331.167
8 J. Crooks C400000100.000
9 V. Scott CF210001000.333

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Brewers vs. Cardinals: Detailed Breakdown

Matchup Overview

  • Teams: Brewers vs. Cardinals
  • Date: Sunday, September 21, 2025
  • Time: 2:15 PM ET
  • Venue: Busch Stadium

Current Betting Odds

  • Spread: Brewers favored at -1.5
  • Total (Over/Under): 8.5
  • Moneyline Odds: Brewers -129, Cardinals +115

Dimers' Win Probabilities

  • Brewers: 53%
  • Cardinals: 47%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Brewers a win probability of 53%, while the Cardinals have a win probability of 47%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Brewers are more likely to beat the Cardinals in the MLB game at Busch Stadium on Sunday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Brewers vs. Cardinals predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.