Cubs vs. Reds Prediction, Picks and Odds

Our detailed prediction and analysis for the Cubs vs. Reds MLB game on September 20, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB sport icon
MLB
Cubs
3
6
Sep 20, 10:40 PM Great American Ball Park
Reds
Sep 20, 10:40 PM Great American Ball Park
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Pro Bets
1 2 3 4 5 6 7 8 9 RHE
Cubs
0 0 1 0 1 0 0 1 0 3 7 0
Reds
0 0 2 0 1 0 1 2 X 6 9 0
Live Probabilities
Moneyline
Over / Under
Run Line
Cubs CHC
Win %
0%
100%
Reds CIN
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Seiya Suzuki strikes out on a foul tip.
Quick Box Score
Hitting
Pitching
Cubs Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 M. Busch 1B41111010.251.250
2 N. Hoerner 2B40200000.51.000
3 I. Happ LF400000200.000
4 M. Ballesteros DH300001100.250
5 D. Swanson SS400000100.000
6 P. Crow-Armstrong CF400000100.000
7 M. Shaw 3B40100000.250.750
8 S. Suzuki PH100000100.000
9 C. Kelly C000000000.000
Reds Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 T. Friedl CF42211010.51.750
2 S. Steer LF41121000.251.250
3 M. Andujar DH20100000.51.000
4 S. Stewart 1B100000100.000
5 N. Marte RF21100000.51.000
6 E. De La Cruz SS30100110.3331.167
7 T. Stephenson C31121110.3331.833
8 K. Hayes 3B400000100.000
9 M. McLain 2B41100010.250.500

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Cubs vs. Reds: Detailed Breakdown

Matchup Overview

  • Teams: Cubs vs. Reds
  • Date: Saturday, September 20, 2025
  • Time: 6:40 PM ET
  • Venue: Great American Ball Park

Current Betting Odds

  • Spread: Reds favored at -1.5
  • Total (Over/Under): 9
  • Moneyline Odds: Cubs -105, Reds -111

Dimers' Win Probabilities

  • Cubs: 51%
  • Reds: 49%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cubs a win probability of 51%, while the Reds have a win probability of 49%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Cubs are more likely to beat the Reds in the MLB game at Great American Ball Park on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cubs vs. Reds predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.