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Guardians vs. Twins Prediction, Picks and Odds

Our detailed prediction and analysis for the Guardians vs. Twins MLB game on September 19, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
Guardians
6
2
Sep 20, 12:10AM Target Field
Twins
Sep 20, 12:10AM Target Field
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Dimers Pro Best Bets
1 2 3 4 5 6 7 8 9 RHE
Guardians
2 0 0 0 0 0 0 2 2 6 9 2
Twins
0 0 0 0 0 2 0 0 0 2 6 0
Live Probabilities
Moneyline
Over / Under
Run Line
Guardians CLE
Win %
100%
0%
Twins MIN
Win Probability
Last At Bat
Outs
Mickey Gasper grounds out to second base, Brayan Rocchio to Jhonkensy Noel.
Quick Box Score
Hitting
Pitching
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 S. Kwan LF52210010.41.000
2 A. Martínez CF50110020.20.600
3 J. Ramírez 3B32100110.3331.267
4 D. Schneemann RF100000100.000
5 B. Naylor C40240000.51.000
6 G. Arias SS40100010.250.750
7 D. Fry DH21100010.51.000
8 J. Noel 1B200000000.000
9 B. Rocchio 2B400000100.000
Twins Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 B. Buxton CF400000200.000
2 A. Martin LF41100010.250.500
3 L. Keaschall 2B41100010.250.750
4 B. Lee SS400000200.000
5 R. Lewis 3B40210020.51.000
6 K. Clemens 1B40100020.250.500
7 T. Larnach DH100000000.500
8 M. Gasper C100000000.000
9 J. Outman RF200001200.333

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Guardians vs. Twins: Detailed Breakdown

Matchup Overview

  • Teams: Guardians vs. Twins
  • Date: Friday, September 19, 2025
  • Time: 8:10 PM ET
  • Venue: Target Field

Current Betting Odds

  • Spread: Guardians favored at -1.5
  • Total (Over/Under): 8
  • Moneyline Odds: Guardians -105, Twins -104

Dimers' Win Probabilities

  • Guardians: 50%
  • Twins: 50%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Guardians a win probability of 50%, while the Twins have a win probability of 50%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Twins are more likely to beat the Guardians in the MLB game at Target Field on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Guardians vs. Twins predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.

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