Reds vs. Cardinals Prediction, Picks and Odds

Our detailed prediction and analysis for the Reds vs. Cardinals MLB game on September 16, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
Start your FREE 3-Day trial of Dimers Pro
FINAL
MLB
Add this game to My Favorites
FINAL
Add this game to My Favorites
MLB sport icon
MLB
Reds
0
3
Sep 16, 11:45PM Busch Stadium
Cardinals
Sep 16, 11:45PM Busch Stadium
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Bets
1 2 3 4 5 6 7 8 9 RHE
Reds
0 0 0 0 0 0 0 0 0 0 3 0
Cardinals
1 0 2 0 0 0 0 0 X 3 8 0
Live Probabilities
Moneyline
Over / Under
Run Line
Reds CIN
Win %
0%
100%
Cardinals STL
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Sal Stewart grounds out to shallow infield, Nolan Arenado to Alec Burleson.
Quick Box Score
Hitting
Pitching
Reds Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 T. Friedl CF300001100.250
2 G. Lux DH40100030.250.750
3 N. Marte RF400000100.000
4 S. Stewart 1B300001000.250
5 W. Benson LF30100010.3330.666
6 T. Stephenson C300000100.000
7 E. De La Cruz SS20100110.51.167
8 K. Hayes 3B300000000.000
9 M. McLain 2B300000100.000
Cardinals Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 B. Donovan 2B41100000.250.750
2 I. Herrera DH40100010.250.500
3 N. Arenado 3B300100000.000
4 A. Burleson 1B41200010.51.000
5 T. Saggese SS41221000.51.750
6 L. Nootbaar LF400000200.000
7 P. Pagés C30200010.6671.334
8 V. Scott CF000000000.000
9 N. Church RF300000200.000

Featured offers

Swipe iconSwipe across to view more offers
logo
FEATURED
New DraftKings Customers: Bet $5, Get $200 in Bonus Bets Instantly
T&Cs apply.
How to claim
logo
RECOMMENDED
Double Your Winnings on your Next 10 Wagers. Up to $25 Max Bet Per Boost
T&Cs apply.
How to claim
logo
NEW PLAYERS
Bet $5, Get $150 in Bonus Bets if your bet wins!
T&Cs apply.
How to claim
logo
RECOMMENDED
Deposit $20, Get $50 in Trading Bonus!
T&Cs apply.
How to claim
logo
LIMITED-TIME
Register with code DIMERS150 to unlock $150 in bonus bets by winning your first $10 bet
T&Cs apply.
How to claim
logo
NEW PLAYERS
Get $350 in Bonus Bets Guaranteed - When You Bet $5 for 7 Days!
T&Cs apply.
How to claim
logo
RECOMMENDED
Use Code DIMERS to Get up to $100 in Bonuses by Trading in Your First 7 Days!
T&Cs apply.
How to claim
logo
TRENDING
Bet $10 Get $365 Win or Lose
T&Cs apply.
How to claim
logo
NEW PLAYERS
Get Up To $250 Back in Bonus Bets If Your First Bet Loses
T&Cs apply.
How to claim

Reds vs. Cardinals: Detailed Breakdown

Matchup Overview

  • Teams: Reds vs. Cardinals
  • Date: Tuesday, September 16, 2025
  • Time: 7:45 PM ET
  • Venue: Busch Stadium

Current Betting Odds

  • Spread: Reds favored at -1.5
  • Total (Over/Under): 3.5
  • Moneyline Odds: Reds +8000, Cardinals +105

Dimers' Win Probabilities

  • Reds: 52%
  • Cardinals: 48%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Reds a win probability of 52%, while the Cardinals have a win probability of 48%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Reds are more likely to beat the Cardinals in the MLB game at Busch Stadium on Tuesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Reds vs. Cardinals predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.