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Cubs vs. Pirates Prediction, Picks and Odds
Our detailed prediction and analysis for the Cubs vs. Pirates MLB game on September 16, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
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MLB
4
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Sep 16, 10:40PM PNC Park
Sep 16, 10:40PM PNC Park
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Bets
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | R | H | E | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cubs | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 14 | 0 |
Pirates | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 |
Live Probabilities
Moneyline
Over / Under
Run Line
Win %
100%
0%
Win Probability
Last At Bat
Outs
Nick Gonzales strikes out on a foul tip.
Quick Box Score
Hitting
Pitching
| No. | Player | Pos | AB | R | H | RBI | HR | BB | SO | AVG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M. Busch | 1B | 4 | 2 | 3 | 1 | 1 | 1 | 0 | 0.75 | 2.800 |
| 2 | N. Hoerner | 2B | 5 | 0 | 3 | 0 | 0 | 0 | 0 | 0.6 | 1.200 |
| 3 | I. Happ | LF | 2 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0.400 |
| 4 | M. Ballesteros | DH | 4 | 1 | 2 | 0 | 0 | 1 | 2 | 0.5 | 1.100 |
| 5 | C. Kelly | C | 5 | 0 | 2 | 0 | 0 | 0 | 1 | 0.4 | 1.000 |
| 6 | P. Crow-Armstrong | CF | 4 | 0 | 1 | 2 | 0 | 0 | 3 | 0.25 | 0.450 |
| 7 | D. Swanson | SS | 4 | 0 | 2 | 0 | 0 | 1 | 1 | 0.5 | 1.100 |
| 8 | W. Castro | RF | 5 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0.000 |
| 9 | M. Shaw | 3B | 4 | 0 | 1 | 0 | 0 | 0 | 2 | 0.25 | 0.500 |
| No. | Player | Pos | AB | R | H | RBI | HR | BB | SO | AVG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | J. Triolo | 3B | 4 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0.000 |
| 2 | S. Horwitz | 1B | 3 | 1 | 1 | 0 | 0 | 1 | 0 | 0.333 | 0.833 |
| 3 | B. Reynolds | DH | 4 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0.000 |
| 4 | O. Cruz | CF | 4 | 0 | 1 | 1 | 0 | 0 | 3 | 0.25 | 1.000 |
| 5 | N. Gonzales | SS | 4 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0.000 |
| 6 | J. Suwinski | LF | 3 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0.000 |
| 7 | N. Yorke | 2B | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.000 |
| 8 | A. Canario | RF | 3 | 0 | 1 | 0 | 0 | 0 | 1 | 0.333 | 0.666 |
| 9 | H. Davis | C | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0.333 | 0.666 |
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Cubs vs. Pirates: Detailed Breakdown
Matchup Overview
- Teams: Cubs vs. Pirates
- Date: Tuesday, September 16, 2025
- Time: 6:40 PM ET
- Venue: PNC Park
Current Betting Odds
- Spread: Pirates favored at -1.5
- Total (Over/Under): 5.5
- Moneyline Odds: Cubs +110, Pirates +8000
Dimers' Win Probabilities
- Cubs: 46%
- Pirates: 54%
Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.
Our Prediction: Who Wins?
After extensive simulations, our model gives the Cubs a win probability of 46%, while the Pirates have a win probability of 54%. Discover the best spread, over/under, and moneyline odds for the game on this page.
Summary
According to our analysis, the Pirates are more likely to beat the Cubs in the MLB game at PNC Park on Tuesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.
Our Cubs vs. Pirates predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.
For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.
