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Guardians vs. Tigers Prediction, Picks and Odds
Our detailed prediction and analysis for the Guardians vs. Tigers MLB game on September 16, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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FINAL
MLB
FINAL
MLB
7
5
Sep 16, 10:40PM Comerica Park
Sep 16, 10:40PM Comerica Park
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Best Bets | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | R | H | E | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Guardians | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 4 | 7 | 13 | 1 |
Tigers | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 5 | 9 | 0 |
Live Probabilities
Moneyline
Over / Under
Run Line
Win %
100%
0%
Win Probability
Last At Bat
Outs
Trey Sweeney lines out to center field to Angel Martínez.
Quick Box Score
Hitting
Pitching
| No. | Player | Pos | AB | R | H | RBI | HR | BB | SO | AVG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | S. Kwan | LF | 5 | 1 | 2 | 1 | 0 | 0 | 0 | 0.4 | 1.000 |
| 2 | A. Martínez | CF | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0.5 | 2.000 |
| 3 | J. Ramírez | 3B | 5 | 2 | 2 | 1 | 0 | 0 | 0 | 0.4 | 1.000 |
| 4 | K. Manzardo | DH | 5 | 0 | 3 | 0 | 0 | 0 | 2 | 0.6 | 1.400 |
| 5 | B. Naylor | C | 5 | 0 | 1 | 1 | 0 | 0 | 2 | 0.2 | 0.600 |
| 6 | G. Arias | SS | 5 | 1 | 2 | 2 | 1 | 0 | 3 | 0.4 | 1.400 |
| 7 | J. Noel | RF | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0.000 |
| 8 | C. Kayfus | 1B | 4 | 0 | 1 | 1 | 0 | 1 | 3 | 0.25 | 0.650 |
| 9 | B. Rocchio | 2B | 4 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 0.000 |
| No. | Player | Pos | AB | R | H | RBI | HR | BB | SO | AVG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | K. Carpenter | DH | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 5.000 |
| 2 | G. Torres | 2B | 5 | 2 | 1 | 1 | 1 | 0 | 1 | 0.2 | 1.000 |
| 3 | W. Pérez | RF | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0.000 |
| 4 | S. Torkelson | 1B | 5 | 1 | 4 | 2 | 1 | 0 | 1 | 0.8 | 2.200 |
| 5 | R. Greene | LF | 4 | 1 | 1 | 0 | 0 | 0 | 1 | 0.25 | 0.650 |
| 6 | T. Sweeney | SS | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.000 |
| 7 | D. Dingler | C | 4 | 0 | 1 | 1 | 0 | 0 | 1 | 0.25 | 0.750 |
| 8 | P. Meadows | CF | 3 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0.250 |
| 9 | Z. McKinstry | 3B | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0.000 |
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Guardians vs. Tigers: Detailed Breakdown
Matchup Overview
- Teams: Guardians vs. Tigers
- Date: Tuesday, September 16, 2025
- Time: 6:40 PM ET
- Venue: Comerica Park
Current Betting Odds
- Spread: Tigers favored at -1.5
- Total (Over/Under): 5.5
- Moneyline Odds: Guardians +120, Tigers +1060
Dimers' Win Probabilities
- Guardians: 44%
- Tigers: 56%
Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.
Our Prediction: Who Wins?
After extensive simulations, our model gives the Guardians a win probability of 44%, while the Tigers have a win probability of 56%. Discover the best spread, over/under, and moneyline odds for the game on this page.
Summary
According to our analysis, the Tigers are more likely to beat the Guardians in the MLB game at Comerica Park on Tuesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.
Our Guardians vs. Tigers predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.
For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.
For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.
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