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White Sox vs. Guardians Prediction, Picks and Odds

Our detailed prediction and analysis for the White Sox vs. Guardians MLB game on September 12, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
White Sox
0
4
Sep 12, 11:10PM Progressive Field
Guardians
Sep 12, 11:10PM Progressive Field
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Dimers Pro Best Bets
1 2 3 4 5 6 7 8 9 RHE
White Sox
0 0 0 0 0 0 0 0 0 0 2 0
Guardians
0 0 0 1 1 0 1 1 X 4 6 1
Live Probabilities
Moneyline
Over / Under
Run Line
White Sox CWS
Win %
0%
100%
Guardians CLE
Win Probability
Last At Bat
Outs
Lenyn Sosa lines out to right field to Nolan Jones.
Quick Box Score
Hitting
Pitching
White Sox Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 M. Tauchman RF400000000.000
2 K. Teel C400000100.000
3 L. Sosa 1B400000300.000
4 C. Montgomery SS300000200.000
5 M. Vargas 3B300000100.000
6 A. Benintendi DH300000200.000
7 M. A. Taylor CF100000000.000
8 C. Meidroth 2B30100000.3330.666
9 W. Robertson LF20100000.51.167
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 S. Kwan LF300001000.250
2 A. Martínez CF31111110.3331.833
3 J. Ramírez 3B400000100.000
4 D. Fry DH31111000.3331.666
5 K. Manzardo 1B300000000.000
6 G. Arias SS31100000.3331.000
7 N. Jones RF101100012.000
8 B. Rocchio 2B300000100.000
9 A. Hedges C30110000.3330.666

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White Sox vs. Guardians: Detailed Breakdown

Matchup Overview

  • Teams: White Sox vs. Guardians
  • Date: Friday, September 12, 2025
  • Time: 7:10 PM ET
  • Venue: Progressive Field

Current Betting Odds

  • Spread: Guardians favored at -1.5
  • Total (Over/Under): 7.5
  • Moneyline Odds: White Sox +123, Guardians -139

Dimers' Win Probabilities

  • White Sox: 41%
  • Guardians: 59%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the White Sox a win probability of 41%, while the Guardians have a win probability of 59%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Guardians are more likely to beat the White Sox in the MLB game at Progressive Field on Friday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our White Sox vs. Guardians predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.

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