Astros vs. D-Backs Prediction, Picks and Odds

Our detailed prediction and analysis for the Astros vs. D-Backs MLB game on July 21, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB sport icon
MLB
Astros
6
3
Jul 22, 1:40 AM Chase Field
D-Backs
Jul 22, 1:40 AM Chase Field
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Pro Bets
1 2 3 4 5 6 7 8 9 RHE
Astros
0 3 1 0 0 0 2 0 0 6 10 1
D-Backs
1 0 1 0 1 0 0 0 0 3 8 0
Live Probabilities
Moneyline
Over / Under
Run Line
Astros HOU
Win %
100%
0%
D-Backs ARI
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Josh Naylor flies out to right field to Cam Smith.
Quick Box Score
Hitting
Pitching
Astros Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 C. Smith RF50100010.20.400
2 J. Altuve DH40100000.250.750
3 V. Caratini C41100010.250.500
4 C. Walker 1B40210000.51.250
5 T. Trammell LF41100020.250.500
6 M. Dubón 3B310001100.250
7 C. McCormick CF41200010.51.000
8 B. Matthews 2B42252020.52.500
9 Z. Short SS400000200.000
D-Backs Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 K. Marte DH41100110.250.900
2 C. Carroll CF51110020.20.400
3 L. Gurriel LF300101000.200
4 E. Suárez 3B41111100.251.400
5 J. Naylor 1B50200010.40.800
6 R. Grichuk RF400000000.000
7 J. McCann C30200100.6671.417
8 B. Alexander 2B20100210.51.750
9 G. Perdomo SS300001000.250

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Astros vs. D-Backs: Detailed Breakdown

Matchup Overview

  • Teams: Astros vs. D-Backs
  • Date: Monday, July 21, 2025
  • Time: 9:40 PM ET
  • Venue: Chase Field

Current Betting Odds

  • Spread: D-Backs favored at -1.5
  • Total (Over/Under): 9
  • Moneyline Odds: Astros +125, D-Backs -139

Dimers' Win Probabilities

  • Astros: 42%
  • D-Backs: 58%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Astros a win probability of 42%, while the D-Backs have a win probability of 58%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the D-Backs are more likely to beat the Astros in the MLB game at Chase Field on Tuesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Astros vs. D-Backs predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.