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Cardinals vs. Guardians Prediction, Picks and Odds

Our detailed prediction and analysis for the Cardinals vs. Guardians MLB game on June 28, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
Cardinals
9
6
Jun 28, 8:10PM Progressive Field
Guardians
Jun 28, 8:10PM Progressive Field
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Dimers Pro Best Bets
1 2 3 4 5 6 7 8 9 RHE
Cardinals
1 0 0 0 2 5 0 0 1 9 14 0
Guardians
0 0 0 6 0 0 0 0 0 6 9 1
Live Probabilities
Moneyline
Over / Under
Run Line
Cardinals STL
Win %
100%
0%
Guardians CLE
Win Probability
Created with Highcharts 10.3.3Inning% ProbabilityCardinalsGuardians0255075100
Created with Highcharts 10.3.3Inning% ProbabilityCardinals +1.5Guardians -1.50255075100
Created with Highcharts 10.3.3Inning% ProbabilityOver 8.5Under 8.50255075100
Last At Bat
Outs
José Ramírez lines out to left center field to Lars Nootbaar.
Quick Box Score
Hitting
Pitching
Cardinals Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 B. Donovan 2B22121200.52.600
2 M. Winn SS51310000.61.400
3 G. Hampson RF000000000.000
4 W. Contreras 1B41211100.52.100
5 L. Nootbaar LF51100030.20.400
6 N. Arenado DH51100010.20.400
7 N. Gorman 3B51210010.40.800
8 Y. Pozo C41100010.250.500
9 V. Scott CF41220000.51.250
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 S. Kwan LF50110000.20.800
2 K. Manzardo DH51211010.41.400
3 J. Ramírez 3B500000100.000
4 C. Santana 1B310001200.250
5 L. Thomas CF41100020.250.750
6 D. Schneemann 2B300101000.250
7 N. Jones RF41210010.51.250
8 G. Arias SS31221110.6672.417
9 B. Naylor C000000000.000

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Cardinals vs. Guardians: Detailed Breakdown

Matchup Overview

  • Teams: Cardinals vs. Guardians
  • Date: Saturday, June 28, 2025
  • Time: 4:10 PM ET
  • Venue: Progressive Field

Current Betting Odds

  • Spread: Guardians favored at -1.5
  • Total (Over/Under): 8
  • Moneyline Odds: Cardinals +105, Guardians -120

Dimers' Win Probabilities

  • Cardinals: 47%
  • Guardians: 53%

Dimers.com's predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cardinals a win probability of 47%, while the Guardians have a win probability of 53%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Guardians are more likely to beat the Cardinals in the MLB game at Progressive Field on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cardinals vs. Guardians predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.

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