Cubs vs. Cardinals Prediction, Picks and Odds

Our detailed prediction and analysis for the Cubs vs. Cardinals MLB game on June 25, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB sport icon
MLB
Cubs
8
0
Jun 25, 11:45PM Busch Stadium
Cardinals
Jun 25, 11:45PM Busch Stadium
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Bets
1 2 3 4 5 6 7 8 9 RHE
Cubs
1 3 1 2 1 0 0 0 0 8 11 1
Cardinals
0 0 0 0 0 0 0 0 0 0 4 1
Live Probabilities
Moneyline
Over / Under
Run Line
Cubs CHC
Win %
100%
0%
Cardinals STL
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Pedro Pagés grounds out to first base, Michael Busch to Porter Hodge.
Quick Box Score
Hitting
Pitching
Cubs Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 I. Happ LF41231120.51.850
2 K. Tucker RF41211120.51.850
3 S. Suzuki DH400001100.200
4 P. Crow-Armstrong CF50100000.20.600
5 D. Swanson SS52200020.41.000
6 M. Busch 1B52210000.40.800
7 J. Berti 2B100000000.000
8 M. Shaw 3B410101000.200
9 R. McGuire C41121010.251.250
Cardinals Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 B. Donovan LF400000100.000
2 J. Fermín 2B101000012.000
3 A. Burleson RF400000000.000
4 V. Scott CF100000000.000
5 P. Pagés 1B100000000.000
6 T. Saggese SS300000000.000
7 N. Gorman 3B30100000.3330.666
8 Y. Pozo C30100000.3331.000
9 G. Hampson P300000000.000

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Cubs vs. Cardinals: Detailed Breakdown

Matchup Overview

  • Teams: Cubs vs. Cardinals
  • Date: Wednesday, June 25, 2025
  • Time: 7:45 PM ET
  • Venue: Busch Stadium

Current Betting Odds

  • Spread: Cubs favored at -1.5
  • Total (Over/Under): 9
  • Moneyline Odds: Cubs -150, Cardinals +135

Dimers' Win Probabilities

  • Cubs: 57%
  • Cardinals: 43%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cubs a win probability of 57%, while the Cardinals have a win probability of 43%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Cubs are more likely to beat the Cardinals in the MLB game at Busch Stadium on Wednesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cubs vs. Cardinals predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.