Cubs vs. Cardinals Prediction, Picks and Odds

Our detailed prediction and analysis for the Cubs vs. Cardinals MLB game on June 25, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.

Unlock all picks and predictions for this game

FINAL

MLB

FINAL

MLB

Cubs

Jun 25, 11:45PM Busch Stadium

Cardinals

Jun 25, 11:45PM Busch Stadium

In-Play ProbabilitiesIn-Play

Game PredictionsPre-Game

Best Bets

	1	2	3	4	5	6	7	8	9	R	H	E
Cubs	1	3	1	2	1	0	0	0	0	8	11	1
Cardinals	0	0	0	0	0	0	0	0	0	0	4	1

Live Probabilities

Moneyline

Over / Under

Run Line

Cubs CHC

Win %

100%

Cardinals STL

Win Probability

Last At Bat

Outs

Pedro Pagés grounds out to first base, Michael Busch to Porter Hodge.

Quick Box Score

Hitting

Pitching

Cubs Hitting

No.	Player	Pos	AB	R	H	RBI	HR	BB	SO	AVG	OPS
1	I. Happ	LF	4	1	2	3	1	1	2	0.5	1.850
2	K. Tucker	RF	4	1	2	1	1	1	2	0.5	1.850
3	S. Suzuki	DH	4	0	0	0	0	1	1	0	0.200
4	P. Crow-Armstrong	CF	5	0	1	0	0	0	0	0.2	0.600
5	D. Swanson	SS	5	2	2	0	0	0	2	0.4	1.000
6	M. Busch	1B	5	2	2	1	0	0	0	0.4	0.800
7	J. Berti	2B	1	0	0	0	0	0	0	0	0.000
8	M. Shaw	3B	4	1	0	1	0	1	0	0	0.200
9	R. McGuire	C	4	1	1	2	1	0	1	0.25	1.250

Cardinals Hitting

No.	Player	Pos	AB	H	SO	AVG	OPS
1	B. Donovan	LF	4	0	1	0	0.000
2	J. Fermín	2B	1	1	0	1	2.000
3	A. Burleson	RF	4	0	0	0	0.000
4	V. Scott	CF	1	0	0	0	0.000
5	P. Pagés	1B	1	0	0	0	0.000
6	T. Saggese	SS	3	0	0	0	0.000
7	N. Gorman	3B	3	1	0	0.333	0.666
8	Y. Pozo	C	3	1	0	0.333	1.000
9	G. Hampson	P	3	0	0	0	0.000

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Cubs vs. Cardinals: Detailed Breakdown

Matchup Overview

Teams: Cubs vs. Cardinals
Date: Wednesday, June 25, 2025
Time: 7:45 PM ET
Venue: Busch Stadium

Current Betting Odds

Spread: Cubs favored at -1.5
Total (Over/Under): 9
Moneyline Odds: Cubs -150, Cardinals +135

Dimers' Win Probabilities

Cubs: 57%
Cardinals: 43%

Dimers.com's predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cubs a win probability of 57%, while the Cardinals have a win probability of 43%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Cubs are more likely to beat the Cardinals in the MLB game at Busch Stadium on Wednesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cubs vs. Cardinals predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.