Southern Miss vs. Louisiana-Lafayette Prediction, Picks and Odds

Southern Miss vs. Louisiana-Lafayette: Detailed Breakdown

Matchup Overview

• Teams: Southern Miss vs. Louisiana-Lafayette
• Date: Saturday, October 18, 2025
• Time: 5:00 PM ET
• Venue: Cajun Field at Our Lady of Lourdes Stadium

Current Betting Odds

• Spread: Southern Miss favored at -4.5
• Total (Over/Under): 54.5
• Moneyline Odds: Southern Miss -182, Louisiana-Lafayette +165

Dimers' Win Probabilities

• Southern Miss: 60%
• Louisiana-Lafayette: 40%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Southern Miss 30-26 Louisiana-Lafayette.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Southern Miss a win probability of 60%, while Louisiana-Lafayette has a win probability of 40%.

Summary

According to our analysis, Southern Miss is more likely to beat Louisiana-Lafayette in CFB action at Cajun Field at Our Lady of Lourdes Stadium on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Southern Miss vs. Louisiana-Lafayette predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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