Syracuse vs. Southern Methodist Prediction, Picks and Odds

Syracuse vs. Southern Methodist: Detailed Breakdown

Matchup Overview

• Teams: Syracuse vs. Southern Methodist
• Date: Saturday, October 4, 2025
• Time: 3:30 PM ET
• Venue: Gerald J. Ford Stadium

Current Betting Odds

• Spread: Southern Methodist favored at -15.5
• Total (Over/Under): 57.5
• Moneyline Odds: Syracuse +590, Southern Methodist -660

Dimers' Win Probabilities

• Syracuse: 14%
• Southern Methodist: 86%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Syracuse 19-36 Southern Methodist.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Syracuse a win probability of 14%, while Southern Methodist has a win probability of 86%.

Summary

According to our analysis, Southern Methodist is more likely to beat Syracuse in CFB action at Gerald J. Ford Stadium on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Syracuse vs. Southern Methodist predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert college football predictions and the best college football bets today for more insights and betting opportunities.

Our in-depth analysis includes college football player props and college football futures, as well as constantly updated college football odds and the latest college football news.