Illinois vs. Indiana Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Illinois vs. Indiana NCAAF game on September 20, 2025. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

FINAL
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Illinois
10
63
Sep 20, 7:30 PM ET Memorial Stadium (Bloomington, IN)
Indiana
Sep 20, 7:30 PM ET Memorial Stadium (Bloomington, IN)
Live Probabilities
Win %
  • Illinois
    0%
  • Indiana
    100%
Win Probability
TEAM1234T
Illinois
7 3 0 0 10
Indiana
14 21 14 14 63
1 0 2 0 3 0 4 0 5 0 4 0 3 0 2 0 1 0 1 0 2 0 3 0 4 0 5 0 4 0 3 0 2 0 1 0
Indiana
Illinois
1st and 10 at the ILL 25
Last Play
G.Wilson rushed for 6 yards. Tackled by ILL at ILL 25.

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Illinois vs. Indiana: Detailed Breakdown

Matchup Overview

  • Teams: Illinois vs. Indiana
  • Date: Saturday, September 20, 2025
  • Time: 7:30 PM ET
  • Venue: Memorial Stadium (Bloomington, IN)

Current betting odds

  • Spread: Indiana favored at -6.5
  • Total (Over/Under): 51.5
  • Moneyline Odds: Illinois +220, Indiana -250

Dimers' win probabilities

  • Illinois: 37%
  • Indiana: 63%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Illinois 24-29 Indiana.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Illinois a win probability of 37%, while Indiana has a win probability of 63%.

Summary

According to our analysis, Indiana is more likely to beat Illinois in CFB action at Memorial Stadium (Bloomington, IN) on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Illinois vs. Indiana predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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Explore our expert college football predictions and the best college football bets today for more insights and betting opportunities.

Our in-depth analysis includes college football player props and college football futures, as well as constantly updated college football odds and the latest college football news.