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James Madison vs. Louisville Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the James Madison vs. Louisville NCAAF game on September 5, 2025. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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James Madison
14
28
Sep 5, 11PM L&N Federal Credit Union Stadium
Louisville
Sep 5, 11PM L&N Federal Credit Union Stadium
In-Play ProbabilitiesIn-Play
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Dimers Pro Best Bets
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James MadisonJMU
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0%
100%
LouisvilleLOU
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TEAM1234T
James Madison
707014
Louisville
0681428
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Louisville
James Madison
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James Madison vs. Louisville: Detailed Breakdown

Matchup Overview

  • Teams: James Madison vs. Louisville
  • Date: Friday, September 5, 2025
  • Time: 7:00 PM ET
  • Venue: L&N Federal Credit Union Stadium

Current Betting Odds

  • Spread: Louisville favored at -12.5
  • Total (Over/Under): 55.5
  • Moneyline Odds: James Madison +550, Louisville -500

Dimers' Win Probabilities

  • James Madison: 17%
  • Louisville: 83%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is James Madison 20-35 Louisville.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives James Madison a win probability of 17%, while Louisville has a win probability of 83%.

Summary

According to our analysis, Louisville is more likely to beat James Madison in CFB action at L&N Federal Credit Union Stadium on Friday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our James Madison vs. Louisville predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert college football predictions and the best college football bets today for more insights and betting opportunities.

Our in-depth analysis includes college football player props and college football futures, as well as constantly updated college football odds and the latest college football news.

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