Clemson vs. South Carolina Prediction, Picks and Odds

Clemson vs. South Carolina: Detailed Breakdown

Matchup Overview

• Teams: Clemson vs. South Carolina
• Date: Saturday, November 29, 2025
• Time: 12:00 PM ET
• Venue: Williams-Brice Stadium

Current Betting Odds

• Spread: South Carolina favored at -2.5
• Total (Over/Under): 46
• Moneyline Odds: Clemson +115, South Carolina -130

Dimers' Win Probabilities

• Clemson: 38%
• South Carolina: 62%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Clemson 22-26 South Carolina.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Clemson a win probability of 38%, while South Carolina has a win probability of 62%.

Summary

According to our analysis, South Carolina is more likely to beat Clemson in CFB action at Williams-Brice Stadium on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Clemson vs. South Carolina predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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