Louisville vs. Tennessee Prediction, Picks and Odds

Louisville vs. Tennessee: Detailed Breakdown

Matchup Overview

• Teams: Louisville vs. Tennessee
• Date: Tuesday, December 16, 2025
• Time: 7:00 PM ET
• Venue: Thompson-Boling Arena

Current Betting Odds

• Spread: Louisville favored at -1.5
• Total (Over/Under): 156.5
• Moneyline Odds: Louisville -110, Tennessee -105

Dimers' Win Probabilities

• Louisville: 53%
• Tennessee: 47%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college basketball matchup is Louisville 79-78 Tennessee.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Louisville a win probability of 53%, while Tennessee has a win probability of 47%.

Summary

According to our analysis, Louisville is more likely to beat Tennessee in CBB action at Thompson-Boling Arena on Wednesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Louisville vs. Tennessee predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert college basketball predictions and the best college basketball bets today for more insights and betting opportunities.

Our in-depth analysis includes college basketball player props and college basketball futures, as well as constantly updated college basketball odds and the latest college basketball news.